TY - JOUR AU - Trung Kien, Pham AU - Nhu Truong, Nguyen AU - Minh Hiep, Nguyen AU - Thi Phuong, Vu PY - 2019/06/21 TI - Symptoms of Neonatal Pneumonia and Results of Its Treatment in Bac Ninh Obstetrics and Pediatrics Hospital JF - VNU Journal of Science: Medical and Pharmaceutical Sciences; Vol 35 No 1DO - 10.25073/2588-1132/vnumps.4162 KW - N2 - This descriptive study describes clinical and subclinical symptoms of neonatal pneumonia and evaluates the results of its treatment in Bac Ninh Obstetrics and Pediatrics Hospital. In this study, 200 children diagnosed with neonatal pneumonia were treated in the hospital from May 1, 2018 to May 1, 2019. Among the patients, 57.0% were male; the male/female ratio was 1.33. There were 67/200 (33.5%) patients aged 0-7 days with 13.5% of whom were preterm neonates. In preterm infants, the most common clinical signs were cough (96.4%), tachypnea (42.9%), wheezing (89.3%), recessive (35.7%), scattered bibasilar rales (85.7%), cyanosis (32.1%), and apnea (21.4%). In full-term infants, the most common symptoms were cough (89.5%), cyanosis (6.9%), recessive (18.6%), and scattered bibasilar rales (77.9%). There were 28.5% of the patients with unstable white blood cells; 26.0% of the children had increased CRP. The most common antibiotic formula was Cefalosporin + Amikacin used in 30% of the cases. 121/200 cultured cases were positive, of which 35.5% was K. pneumoniae , 27.3% was H.influenzae , 21.5% was E.coli , and 14.0% was S.aureus . The average duration of treatment was 8.6 ± 3.8 days. The study concludes that neonatal pneumonia was more common in male children; the main clinical manifestations were coughing, rapid breathing, small granules; and a combination of antibiotics was effective in treating neonatal pneumonia. Keywords Neonatal pneumonia, tachypnea, apnea, use of antibiotics. References [1] Khu Thị Khánh Dung, Nghiên cứu đặc điểm lâm sàng vi khuẩn và một số yếu tố liên quan đến viêm phổi sơ sinh, Luận án Tiến sĩ Y học, Trường Đại học Y Hà Nội, (2003). [2] Nguyễn Tuấn Ngọc, Cơ cấu và căn nguyên nhiễm khuẩn sơ sinh tại Khoa Nhi Bệnh viện Đa khoa Trung ương Thái Nguyên, Tạp chí Y học thực hành. 678 (2009) 7-10. [3] Friedrich Reiterer, Neonatal Pneumonia, in: B.Resch, Neonatal Bacterial Infection, Intech Open, London, 2013, pp.20 - 32. [4] Chao-Jen Lin and et.al, Radiographic, clinical, and prognostic features of complicated and uncomplicated community-acquired lobar pneumonia in children, J Microbiol Immunol Infect. 39 (2007) 489-495. [5] David Martin le Roux, Heather Zar, Community-acquired pneumonia in children - a changing spectrum of disease, Pediatric Radiology. 47 (2017) 1392 – 1398. https://doi.org/10.1007/s00247-017-3827-8. [6] Sreekumaran Nair, Leslie Edward Lewis, and et.al, Factors associated with neonatal pneumonia in India: protocol for a systematic review and planned meta-analysis, BMJ Open. 8 (2018) 1-5. https://doi.org/10.1136/bmjopen-2017-018790. [7] Nguyễn Thị Kim Anh, Phạm Thị Minh Hồng, Đặc điểm viêm phổi sơ sinh tại bệnh viện Nhi Đồng 2 từ 3/2007 đến 10/2007, Tạp chí Y học Thành Phố Hồ Chí Minh. 13 (2009), 1-7. [8] Lihong Yang and et.al, Prevalence and risk factors of neonatal pneumonia in China: A longitudinal clinical study, Biomedical Research. 29 (2018) 57 - 60. [9] Shah Shetal and et.al, Factors associated with mortality and length of stay in hospitalised neonates in Eritrea, Africa: a cross-sectional study, BMJ Open. 2 (2012) 1-9. https://doi.org/10.1136/bmjopen-2011-000792. [10] Đỗ Thị Bích Vân và cộng sự, Nhận xét kết quả của vỗ rung liệu pháp trong điều trị viêm phổi sơ sinh không thở máy tại Bệnh viện Nhi Trung ương, Tạp chí Y học Thành Phố Hồ Chí Minh. 16 (2012) 93-97. [11] Vũ Thị Phương, Nghiên cứu nguyên nhân vi khuẩn gây bệnh, kết quả điều trị và một số yếu tố liên quan đến tử vong trong viêm phổi sơ sinh tại bệnh viện Trẻ em Hải Phòng năm 2011, Luận văn Thạc sĩ y học, Trường Đại học Y Hải Phòng (2012).   UR - https://js.vnu.edu.vn/MPS/article/view/4162