TY - JOUR AU - Phu Hung, Luong AU - Thi Van Anh, Nguyen AU - Tien Dung, Do AU - Thi Thom, Vu PY - 2020 TI - Platelet Aggregation Activities of Vietnamese Medicinal Plants: Anti-Thrombolytic Potentials? JF - VNU Journal of Science: Medical and Pharmaceutical Sciences; Vol 36 No 2 DO - 10.25073/2588-1132/vnumps.4252 KW - N2 - Blood coagulant, an important physiological process, underlines pathology of various diseases. Thrombosis caused by activated platelets in blood stream can lead to narrowing or blocking the blood flow, which results in stroke or ischemic conditions. The number of human deaths caused by coronary disease or stroke has been increasing rapidly over the last few years in Vietnam. Many anti-thrombosis and anti-platelet aggregation drugs have been discovered and applied in treatment. However, these drugs have many side effects such as bleeding, stomach lesion, etc. Vietnam is a tropical country with plenty of medicinal plants, from which a potential drug for anti-thrombolytic activities can be prepared. Therefore, an overview of Vietnamese medicinal plants with anti-platelet aggregation activities, such as Panax L., Canna , is highly needed for improving the quality of exploiting Vietnamese medicinal resources. Keywords Anti-thrombosis, Canna, Panax L., platelet aggregation, Vietnamese medicinal plants. References [1] P.T.M. Duc, Physiology, Vietnamese Medical Publisher, 2006 (in Vietnamese). [2] S. H. Yun, E.H. Sim, R.Y. Goh, J.I. Park, J.Y. Han, Platelet Activation: The Mechanisms and Potential Biomarkers, Biomed Res Int, 2016. https://doi.org/10.1155/2016/9060143. [3] E.K. Shin, H. Park, J.Y. Noh, K.M. Lim, J.H. 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