Efflux Pumps and These Inhibitors

Abstract

 In this era of multi-drug resistance, efflux pump is one of the major problems which is increasingly concerned by scientists. The structure and mechanism activity of the efflux pumps on both bacteria and eurakyotes that are gradually being clarified. Since then, efflux pump inhibitors have also been studied and initially applied in clinic, that makes an important contribution to preventing the outbreak of multi-resistant infections and cancers. Efflux pump inhibitors are often small synthetic molecules or plant metabolites that show great promise in inhibiting multi- resistant in both bacteria and cancerous cells.

Keywords

Efflux pump, EPI, bacteria, cancer, MRD.

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