Developing a Process of Preparing Fallopia multiflora Thunb. and Proposing Basic Standards for the Product

Abstract

Fallopia multiflora Thunb. is a precious remedy in traditional medicine of many countries. In terms of chemical composition, emodin (EM) and 2,3,5,4′-tetrahydroxystilben-2-O-β-D-glucoside (THSG) were identified as chemical markers of Fallopia multiflora Thunb. This study was conducted to develop a preparing process that helps to minimize the THSG content while increasing the ratio between EM and THSG. The HPLC-DAD method was used to quantify these substances in the raw materials and samples after each processing stage to investigate the effects of the different processing conditions. It is found that the process of preparing Fallopia multiflora Thunb. can reduce at least 53% of THSG. The ratio of EM to THSG increased by more than 2.6 times after the processing. The process has many advantages, such as simplicity, no need of soaking the herb in rice water, and short processing time. The standards with such criteria as description, identification, loss on drying, extract, and assay for the prepared product were also proposed.

Keywords:

Fallopia multiflora Thunb., processing mechanism, emodin, 2,3,5,4′-tetrahydroxystilben-2-O-β-D-glucoside.

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