Evaluating the GALAD Score in Diagnosing Hepatocellular Carcinoma

Abstract

This paper aims to evaluate the GALAD score in diagnosing hepatocellular carcinoma. The paper conducted a retrospective study of 86 Hepatocellular Carcinoma patients who underwent AFP, AFP-L3, and PIVKA II. The results show that the average age of the patients was 57.7 ± 11.14, the ratio of male/female was 11.34/1. The median values of AFP, AFP-L3, and PIVKA-II before treatment were 196 ng/mL, 16.2%, and 3154.5 mAU/mL, respectively. The sensitivity of AFP, AFP-L3, and PIVKA-II was 80.2%; 58.1%; and 88.4%, respectively. The combination of the three markers also showed a high sensitivity of 94.2%. The mean value of GALAD in the patients was 5.83 ± 5.3. The liver cancer probability index was 0.8485 ± 0.276. Overall, the paper results suggest that using the BALAD score is both easy to practice and economical, which is highly useful for the early detection of hepatocellular carcinoma.

Keywords:

Hepatocellular carcinoma, PIVKA-II, GALAD score.

References

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