A Review of Therapeutic Drug Monitoring and Model-Informed Precision Dosing in Personalized Medicine

Bui Son Nhat, Le Thi Luyen

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Published Dec 18, 2022
DOI: https://doi.org/10.25073/2588-1132/vnumps.4378

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How to Cite
SON NHAT, Bui; THI LUYEN, Le. A Review of Therapeutic Drug Monitoring and Model-Informed Precision Dosing in Personalized Medicine. VNU Journal of Science: Medical and Pharmaceutical Sciences, [S.l.], v. 38, n. 4, dec. 2022. ISSN 2588-1132. Available at: <https://js.vnu.edu.vn/MPS/article/view/4378>. Date accessed: 21 nov. 2024. doi: https://doi.org/10.25073/2588-1132/vnumps.4378.
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Issue
Vol 38 No 4
Section
Review Articles

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Abstract

Therapeutic drug monitoring (TDM) and model-informed precision dosing (MIPD) have become effective methods in determining and adjusting dose regimens of various drugs in clinical practice. With the latest development in technology, particularly in computer science, drug individualization has evolved to be more flexible and precise. However, these methods still have certain drawbacks and have not been applied on a grand scale. This review shall present the most basic concept of TDM and MIPD as well as current issues in their application.