Microsponges-Application in Pharmaceutics

Abstract

 Microsponges are spherical particle systems with many channels and pores on the surface and inside, typically measuring less than 300 μm in diameter. Compared to conventional dosage forms, microsponges offer controlled drug release, improved bioavailability, reduced side effects, and enhanced solubility of poorly water-soluble drugs. Their porous structure enables high drug-loading capacity for both hydrophobic and hydrophilic drugs. This article provides an overview of microsponges, including an introduction and composition of microsponges, methods of microsponges preparation (liquid-liquid suspension polymerization and quasi-emulsion solvent diffusion method), and potential applications of microsponges in pharmaceutics. This information is expected to contribute effectively to the research and development of advanced drug delivery systems.