Ngo Thi Trang, Nguyen Thanh Luan, Pham Thi Luong Hang

Main Article Content

Abstract

Abstract: The purpose of this study was to propagate the japanese honeysuckle species (Lonicera japonica Thunb.)  via callus formation. We described callus induction in young leaves and shoot tip explants of this species, their proliferation and shoot regeneration from the callus. Both explants were cultured on MS medium supplemented with growth plant regulators (2.4-D; NAA and BAP) for callus induction. Our results showed that callus formation from shoot tip explants was better than that  from leaf explants with white in color and soft callus when cultured on MS medium containing 1.5 mg/l of BAP. Callus formation from this medium was 92.31% successful with an average length size of 1.8 cm. After four weeks of callus induction in a completely dark condition, calli were transferred for two weeks to brightly light conditions for callus proliferation on MS medium supplemented with 0.5 mg/l of BAP in which calli increased five times in size. Calli were luxuriant and pale green in color. Shoots were regenerated from the callus on MS medium containing 1 mg/l of BAP in which 100% of cultured callus pieces produced adventitious shoots with shoot numbers ranging from 14 to 20 per callus.

Keywords: Callus, in vitro propagation, Lonicera japonica, medicinal plant.

References

References
[1] Đỗ Tất Lợi, Những cây thuốc và vị thuốc Việt Nam, Nhà xuất bản Khoa học và Kỹ thuật, Hà Nội, 1991.
[2] Võ Văn Chi, Từ điển cây thuốc Việt Nam, Nhà xuất bản Y học, Hà Nội và TP Hồ Chí Minh, 1997.
[3] X. Shang, H. Pan, M. Li, X. Maio and H. Ding, Lonicera japonica Thunb.: Ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine. Journal of Ethnopharmacology, Vol. 138, issue 1 (2011) 1.
[4] A. Rahman and S.C. Kan, In vitro control of food-borne and food spoilage bacteria by essential oil and ethanol extracts of Lonicera japonica Thunb. Food Chemistry 116 (2009) 670.
[5] J. Xiong, S. Li, W. Wang, Y. Hong, K. Tang and Q. Luo, Screening and identification of the antibacterial bioactive compounds from Lonicera japonica Thunb., Food chemistry 138 (2013) 327.
[6] W. Ning, et al., Enhanced secondary metabolites production and antioxidant activity in postharvest Lonicera japonica Thunb. in response to UV radiation, Innovative Food Science & Emerging Technologies 13 (2012) 231.
[7] J.H. Lee, W.S. Ko, Y.H. Kim, H.S. Kang, H.D. Kim and B.T. Choi, Anti-inflammatory effect of the aqueous extract from Lonicera japonica flower is related to inhibition of NF-kappaB activation through reducing I-kappaBalpha degradation in rat liver, International Journal of Molecular medicine 7 (2001) 79.
[8] R. Lanteri, R. Acquaviva, C. DiGiacomo, V.L. Sorrenti, G.Destri, M. Santangelo, L. Vanella and A. DiCataldo, Rutin in rat liver ischemia/reperfusion injury: effect on DDAH/NOS pathway, Microsurgery 27 (2007) 245.
[9] W.C. Chang and F.L. Hsu, Inhibition of platelet activation and endothelial cell injury by polyphenolic compounds isolated from Lonicera japonica Thunb. Prostag Leukotr Ess. 45 (1992) 307.
[10] K.H. Son, K.Y. Jung, H.W. Chang, H.P. Kim and S.S. Kang. Triterpenoid saponins from the aerial parts of Lonicera japonica. Phytochemistry. 35 (1994) 1005.
[11] Phan Minh Giang, Nguyễn Tuấn Minh, Phan Tống Sơn, Phytochemical investigation and study on cytotoxic and antimicrobial activites of Lonicera japonica Thumb., Caprifoliaceae, of Vietnam. Journal of Chemistry, Vol. 40, No. 3, (2002) 103.
[12] Phạm Minh Giang, Nguyễn Tuấn Minh, Nguyễn Minh Hằng, Phan Tống Sơn, Nghiên cứu hoạt chất sinh học từ cây kim ngân (Lonicera japonica Thunb., Caprifoliaceae) của Việt Nam. Kỷ yếu hội nghị khoa học và công nghệ Hóa hữu cơ toàn quốc lần thứ III, Hội hóa học Việt Nam, phân hội Hóa hữu cơ, (2005) 318.
[13] Lê Thị Diễm Hồng, Nguyễn Thị Hồng Nhiên, Nguyễn Thị Hồng Vân, Nguyễn Viết Thân và Nguyễn Xuân Thắng, Nghiên cứu tác dụng chống viêm mạn của saponin và flavonoid cây kim ngân (Lonicera japonica Thunb.), Tạp chí Dược học, số 378 (2007) 24.
[14] Nguyen Thi Thanh Mai, S. Awale, Y. Tezuke, Tran Le Quan, H. Watanabe and S. Kadota, Xanthine oxidase inhibitory activity of Vietnamese medicinal plants. Biol. Pharm. Bull. 27(9) (2004) 1414.
[15] T. Murashige and F. Skoog. A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol. Plant. 15 (1962) 473.
[16] D. Georges, J. Chenieux and S. Ochatt. Plant regeneration from aged-callus of the woody ornamental species Lonicera japonica cv. ‘Hall’s prolific’. Plant Cell Rep. 13 (1993) 91.
[17] X.Wang, J. Chen, Y. Li, Q. Nie and J. Li. An Efficient Procedure for Regeneration from Leaf-derived Calluses of Lonicera macranthoides ‘Jincuilei’, an Important Medicinal Plant. Hortscience 44 (2009) 746.
R.M. Patel and R.R. Shah. Regeneration of Stevia plant through callus culture. Indian Journal Pharmaceut. Sci. 71 (2009) 46.