Study on haplotype diversity of Y-STR loci of the Kinh population in Vietnam
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Abstract
The study was carried out to determine allele frequencies of Y-STRloci in order to apply in the statistical validation of forensic case and paternal lineages. 17 Y-STR loci were co-amplified (including: DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, and GATAH4) using DNA genome extracted from blood, hair root and finger nail samples of 205 unrelated men of Kinh population in the North and South of Vietnam.
The studied population shows that a relatively close relationship between the Jiangxi (Han) and Jiangsu (Han) populations in China and the Han population in Taiwan. Compared to other population with geographic locations far removed from Vietnam and historically and culturally diverse, there are significant differences as with Americans (Rst = 0.3836, P <0.0001); The Germans (Rst = 0.3562, p = -1.0000); The Romans (Rst = 0.2918, p = -1.0000) or Ethiopian (Rst = 0.3139, p = -1.0000) and particularly significant differences with Nigerians (Rst = 0.5084, p = -1.0000).
The genetic diversity indexes at each locus and the haplotypes were examined; Genetic distances between the King population in this study and neighboring populations and geographically remote populations are consistent with the migration history.
References
[2] Butler JM,Recent developments inY-short tandem repeat and Ysingle nucleotide polymorphism analysis, Forensic Science Rev, 2003,15:91-111.
[3] Gusmao L, Butler JM, Carracedo A, Gill P, Kayser M, DNA commission of the international Society of Forensic Genetics (iSFG): an update of the recommendations on the use of Y-Strs in forensic analysis, Forensic Sci Int. 2006,157:187-97.
[4] Roewer l, Krawczak M, Willuweit S, nagy M, Alves C, Amorim A.Online reference database of european Y-chromosomal shorttandem repeat (Str) haplotypes, Forensic Sci Int. 2001, 118:106-13.
[5] Walsh PS, Metzger DA, Higuchi R.Chelex 100 as a medium for simple extraction of DNA for PCR-based typing fromforensic material. Biotechniques. 1991,10:506-13.
[6] Excoffier L, Laval G, Schneider S.An integrated software package for population genetics data analysis. Evol Evol Bioinform Online. 2005; 1: 47–50.