Synthesis, Structural Characterization of 4’,4’’-Dibenzoylcurcumin and Assessment of its Complexation with Fe3+ and Cu2+

Abstract

The curcumin derivative 4’,4’’-dibenzoylcurcumin (HL) was synthesized by the reaction between curcumin and benzoyl chloride in the presence of pyridine as a supporting base. The composition and structure of HL were characterized by spectroscopic methods such as IR, 1H and 13C NMR spectroscopy. Reactions of HL and transition metal ions, such as Fe3+ and Cu2+, in mixtures of CH3OH and CH2Cl2 gave rise to the corresponding complexes, compositions and structural features of which were studied by thermal analysis and IR spectroscopy. The results strongly suggested the obtained complexes with the compositions of [FeL3] and [CuL2]. In such compounds, metal ions coordinates with the deprotonated ligands L– through the donor sets (O,O) of the keto-enol moieties.
Keywords: Curcumin, 4’,4’’-dibenzoylcurcumin, β-diketone, Fe(III) complexes, Cu(II) complexes.

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